Dopamine is widespread in the brain as well as the rest of the nervous system. This neurotransmitter plays a critical role in the control of movement. It has a stimulating effect on the heart, the circulation, the rate of metabolism, and is able to mobilize many of the body's energy reserves. It helps to modulate brain activity, control coordination and movement, and regulate the flow of information to different areas of the brain. Dopamine is believed to release chemicals that allow us to feel pleasure (e.g., endorphins). A massive disturbance of dopamine regulation in the brain can result in a person no longer being able to respond emotionally or express his or her feelings in an appropriate way
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cactus.nci.nih.gov/ncidb/PASS_Predictions.lst
78322 2,3-Oxidosqualene-lanosterol cyclase inhibitor 125857 3 Hydroxyanthranilate oxygenase inhibitor 25482 5 Alpha reductase inhibitor 8283 5 Hydroxytryptamine 1 agonist 14271 5 Hydroxytryptamine 1 antagonist 10341 5 ... 11970 Dopamine antagonist 7942 Dopamine autoreceptor agonist 40178 Dopamine beta hydroxylase inhibitor 44719 Dopamine ... bile acid transport inhibitor 77450 Immunomodulator ...
Appendix A: List of Activity Types
... d1 antagonist dopamine d2 antagonist dopamine d2 antagonist dopamine-d2 agonist dopaminergic dopaminergic ... a2 norepinephrine antagonist nucleoside transport inhibitor null null ...
Dio1 - Type I iodothyronine deiodinase
The following synonyms exist for gene Dio1 (Type I iodothyronine deiodinase): D1, Type-I 5'deiodinase, DIOI, Type 1 DI, 5DI, Txdi1, Itdi1. ... activity and mitochondrial phosphate transport in Hyp mice. ... a mixed dopamine (DA) agonist in male Swiss-Webster mice, was not blocked by the selective D-1 antagonist SCH 23390 ...
Permuted activity index
Permuted activity index a1 adrenergic agonist a1 adrenergic antagonist... synthesis inhibitor fatty acid transport inhibitor amino acid essential ... antagonist dopamine d3 agonist dopamine d3 antagonist dopamine d4 antagonist dopamine d1/d5 antagonist anti ...
Novascreen - Standard Services: Cellular Functional Assays
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