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Dopamine is widespread in the brain as well as the rest of the nervous system. This neurotransmitter plays a critical role in the control of movement. It has a stimulating effect on the heart, the circulation, the rate of metabolism, and is able to mobilize many of the body's energy reserves. It helps to modulate brain activity, control coordination and movement, and regulate the flow of information to different areas of the brain. Dopamine is believed to release chemicals that allow us to feel pleasure (e.g., endorphins). A massive disturbance of dopamine regulation in the brain can result in a person no longer being able to respond emotionally or express his or her feelings in an appropriate way

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